Episcreen T cell assay technology for biologics www.antitope.co.uk Scientists have discovered one of the reasons why many previous attempts to harness the immune system to treat cancerous tumours have failed - a feat that could revolutionise cancer therapy. University of Cambridge scientists revealed that a type of stromal cell found in many cancers which expresses fibroblast activation protein alpha (FAP), plays a major role in suppressing the immune response in cancerous tumours - thereby restricting the use of vaccines and other therapies, which rely on the body's immune system to work. They have also found that if they destroy these cells in a tumour immune suppression is relieved, allowing the immune system to control the previously uncontrolled tumour. "Finding the specific cells within the complex mixture of the cancer stroma that prevents immune killing is an important step. Further studying how these cells exert their effects may contribute to improved immunol...